HIGHLIGHTS
- Strong executive background with over 10 years of experience in setting up companies and running businesses
- Strong management skills with 7 years of experience as a medical research project manager
- Familiarity with GCP and ICH guidelines, including a basic understanding of regulatory requirements
- Familiarity with clinical trial process with 5+ years of experience in clinical research and 10+ years of experience in medical research.
- Strong data analysis skills.
- Excellent organization, planning and problem solving abilities.
- Excellent negotiation and analytical skills.
EDUCATION
- B. S. Biochemistry, Jilin University, Changchun, P.R. China, 1984
- Ph. D. Biomedical, Dalian Medical University, Dalian, P.R. China, 1996
LICENSURE
- CLSp (MB) Certified Clinical laboratory specialist in molecular biology,NCA, USA. 2003
TRAINING
- Postdoctoral, Clinical Pathology Lab, Research Institute, 03/96-03/98
William Beaumont Hospital, MI 48073
WORK AND MANAGEMENT EXPERIENCES
President
Yurise Foundation, Houston, TX 77036(09/22-Current)
- Serves as the organization’s primary spokesperson by leading key public engagements, and nurturing relationships within the community.
- Works closely with the Yurise board to develop strategy, identify opportunities, address issues, and develop recommendations to further the organization’s impact.
- Oversees communication with internal/external stakeholders, ensuring messaging amplifies the organization’s mission, programs, and impact in accordance with the organization’s values
- Exhibits sound fiscal budget management, with maximum resource utilization and maintenance of the organization’s positive financial position.
- Dedicates significant attention to fundraising initiatives and activities in partnership with the Fund Development team.
- Demonstrate cultural awareness and actively foster an inclusive, culturally sensitive environment. Willingness to ask questions, learn, and constructively share and accept feedback.
- Develops a diverse team of staff and volunteers who reflect the community they serve, and support the organization’s mission, goals, and core values.
Chief Executive Officer (CEO)
CHM BioHealth LLC, Austin, TX 78750 9/13-Current)
- Establishing overall direction and strategic initiatives for the given major function or line of business
- Establishing financial goals and profitability
- Developing Bio Health Programs and operational standards
- Directs and coordinates the business operation
- Report to a board of directors
- Managing a business unit, division or corporate function with major organizational impact
Chief Operation Officer (COO)
CHM Adult Care Center, Austin, TX 78681(06/13-11/18)
- Participate in application for a license from Texas Department of Aging and Disability Services
- Consultation of medical knowledge
Clinical Trial Principle Investigator
Karmanos Cancer Institute, National Center of Vermiculite and Asbestos (NCVAC) Wayne State University, Detroit, MI 48201 (04/08-09/13)
Biomarker trial for the diagnosis of mesothelioma with experiences in:
- Hiring and training research associates and assistants
- Designing and planning the research project
- IRB application
- Writing and modification of protocols
- Development of informed consent documents
- Recruitment and enrollment of human subjects
- Participant interviews
- Specimen processing
- Establishing blood bank and blood testing
- Data collection and analysis
- Writing project progress report
- Grant and budget development
Clinical Research Assistant Professor
Internal Medicine, Wayne State University, Detroit, MI (04/04-04/12)
Early diagnosis of breast cancer study with the experiences in:
- Design and planning of the breast cancer research project
- Supervising research associates and assistants
- Developing and modifying protocol
- Quality Control
- Writing progress reports
- Training residents and postdoctoral in clinical research
- Collecting data and performing data analysis
- Making and controlling the budget
- Patient specimen collection
- Performing all the research work in the lab
Lab Manager and Research Associate, Clinical Pathology
William Beaumont Hospital, Royal Oak, MI. (1996-1999)
- Development and modification of molecular protocols of MPO test for clinical diagnosis of leukemia.
Lab Manager and Research Associate
- Molecular Biology Laboratory, Cardiovascular Institute, Beijing Medical University, Beijing, China (09/90- 07/93)
- Design and plan the research project
- Develop and modify protocols
- Supervise research associates and assistants
- Quality Control
- Data analysis
- Write progress report
Group Leader of Union
Department of Biochemistry, Dalian Medical University, Dalian, Liaoning, P.R. China, (09/88-07/90)
Assistant of Chair
Department of Biochemistry, Dalian Medical University, Dalian, Liaoning, P.R. China, (09/86-07/90)
- Assist Chair in making teaching and medical research plans
- Collaborate and communicate with other departments
- Write the annual report
FUNDINGS
National Cancer Institute SBIR Contract Phase 2 (HHSN261201200043C)
N. Tang, CO-PI
“Photonic Crystal Microarray nano-platform for high throughput highly sensitive and highly specific detection and identification of cancers” $1,000,000 (5% Effort), 9/30/2012-09/30/2014
US Army ECBC SBIR Contract (W911SR-12-C-0046)
N. Tang, CO-PI
“Monolithic photonic crystal on-chip absorption spectrometer for laser absorption spectroscopy” Phase 2,
$780,000 (5% Effort) 05/03/2012-05/02/2014
NIH/ NIEHS Grant, Phase 2 (9R42ES024023)
N. Tang, CO-PI
“Resonant-Photonic-Device-Enhanced SERS Substrates with Pinpointed Plasmonic-Active Nanotubes for Ultrasensitive Biomolecule Detection”
$1,000,000 (5% Effort), 09/15/2013-08/30/2015
Breath of Life foundation, NCVAC #026-129
N. Tang, PI
“New biomarkers discovery and the molecular mechanisms of carcinogenesis for Mesothelioma among Asbestos exposed Populations”
$200,000, 2010-2012.
NIH-RO1.CA122277
N. Tang Co-investigator. F. Fernández Madrid PI.
“Development and validation of an autoantigen panel for the diagnosis of
breast cancer”
$ 1,670,000, 9/2008-8/2011
U.S. Environmental Protection Agency (2006-057)
N Tang, sub project PI
National Center for Vermiculite and Asbestos-related Cancers---
“Early Detection Biomarkers for Mesothelioma among Asbestos and
Vermiculite exposed Populations,"
$1,000,000, 3/2006-2/2010
NIH: R21 AR-99-128 (CA-87759-02)
Tang N, Co-Investigator. F. Fernández-Madrid, PI.
“Autoantibody to Nuclear Antigens as Markers of Breast Cancer”
$223,500, 03/2001 – 02/2003
COLLABRATION WITH CHINA
1.Zhongshan Hospital, Dalian University, Dalian, Liaoning, P.R. China (2012)
Early diagnosis for breast Cancer
2. Tianjin Tumor Hospital, Tianjin, P.R. China (2010)
Early diagnosis for breast cancer
3. Shandong Medical Institute, Jinan, Shandong, P.R. China (2001)
Cancer Drug development and animal study
SELLECTED PUBLICATIONS
- Hai Yan, Chun-Ju Yang,Naimei Tang, [...], Ray T Chen, “Specific Detection of Antibiotics by Silicon On-chip Photonic Crystal Biosensor Arrays,” Aug 2017
- Lijun Huang, Hai Yan, Xiaochuan Xu, Swapanajit Chakravarty, Naimei Tang, Huiping Tian, and Ray Chen, “Improving the detection limit for on-chip photonic sensor based on subwavelength grating racetrack resonators,” Optics Express, Vol.25, No.9, pp.10527- 10535, 2017.
- Swapnajit Chakravarty, Xiangning Chen, Naimei Tang… Ray Chen, “Review of design principles of 2D photonic crystal microcavity biosensors in silicon and their applications,” Frontiers of Optoelectronics 9(2):206-224, June 2016
- Hai Yan, Naimei Tang, Grace A. Jairo, [...], Ray T Chen, ”High-sensitivity high-throughput chip based biosensor array for multiplexed detection of heavy metals. Conference Paper, Mar 2016
- Hai Yan, Lijun Huang, Xiaochuan Xu, Swapnajit Chakravarty, Naimei Tang, Huiping Tian, and Ray T. Chen, "Unique surface sensing property and enhanced sensitivity in microring resonator biosensors based on subwavelength grating waveguides," Opt. Express 24, 29724-29733 (2016).
- H. Yan, Y. Zou, S. Chakravarty, C.-J. Yang, Z. Wang, N. Tang, D. Fan and R. T. Chen., "Silicon on-chip bandpass filters for the multiplexing of high sensitivity photonic crystal microcavity biosensors," Applied Physics Letters, vol. 106, p. 121103, 2015.
- Chun-Ju Yang, Naimei Tang, Hai Yan[...], Ray Chen. 193nm Lithography Fabricated High Sensitivity Photonic Crystal Microcavity Biosensors for Plasma Protein Detection in Patients with Pancreatic Cancer. CLEO, OSA Technical Digest (online) Optical Society of America, May 2015.
- Xinbo Zhang*, Naimei Tang*, Crystal S Zhang, Shihong Mao, Anil Wali, Harvey Pass, Felix Fernandez-Madrid, Michael R Harbut and Ann G Schwartz. Counterintuitive features of side population cells in mesothelioma. Submitted to BMC Cancer, December 2012
- Crystal Siyu Zhang1, Xinbo Zhang2, Felix Fernandez-Madrid2, Harvey Pass3, Ann Swartz2, 4, Michael Harbut5, Naimei Tang2,5, Identification of an autoantibody panel as a potential signature of malignant pleural mesothelioma. 11th International Conference of the International Mesothelioma Interest Group (iMig 2012), Oral presentation, Boston, September 11 – 14, 2012
- Zhang X, Zhang SC, Sun D, Hu J, Wali A, Pass H, Fernandez-Madrid F, Harbut MR, Tang N*. New insight into the molecular mechanisms of the biological effects of DNA minor groove binders. PLoS ONE. 6(10):e25822 2011.
- Zhang X, Tang N, Hadden TJ, Rishi A. Akt, FoxO and regulation of apoptosis. Biochim Biophys Acta. 1813:1978-1986, 2011.
- Tang N, Zhang X, Pass H, Wali A, Madrid F, Schwart A, and Harbut M. Differential gene expression profiles of side population cells from Mesothelioma cell lines. 2010 ASCO- NCI – EORTC Annual Meeting on Molecular Markers in Cancer. Hollywood, Florida, October 18 -20, 2010.
- Madrid F*, Chen W, Tang N, Zhang X, Dong J, Sagar H and Abrams J. Autoantibodies in Breast Cancer Identify Proteins Involved in Self-Renewal and Epigenetic Chromatin Remodeling. The Open Biomarkers Journal, 3, 1-8, 2010
- Pass HI, Wali A, Tang N, Ivanova A, Ivanov S, Harbut M, Carbone M, Allard J. Soluble mesothelin-related peptide level elevation in mesothelioma serum and pleural effusions. Ann Thorac Surg. 85(1):265-72; discussion 272, 2008.
- Harvey I. Pass, Dan Lott, Fulvio Lonardo MD, Michael Harbut , Zhangdong Liu , Naimei Tang PhD*, Michele Carbone, Craig Webb, and Anil Wali. Asbestos Exposure, Pleural Mesothelioma, and Serum Osteopontin Levels. NEJM 353:1564-73, 2005.
- Fernandez Madrid F, Karvonen RL, Ensley J, Kraut M, Granda JL, Alansari H, Tang N, Tomkiel JE. Spectra of antinuclear antibodies in patients with squamous cell carcinoma of the lung and of the head and neck. Cancer Detect Prev. 29: 59-65, 2005.
- Fernandez Madrid F, Tang N, Alansari H, Karvonen RL, Tomkiel JE. Improved approach to identify cancer-associated autoantigens. Autoimmun Rev. 4: 230-5, 2004.
- Fernandez-Madrid F, Tang N, Alansari H, Granda JL, Tait L, Amirikia KC, Moroianu M, Wang X, Karvonen RL. Autoantibodies to Annexin XI-A and Other Autoantigens in the Diagnosis of Breast Cancer. Cancer Res, 64:5089-96, 2004.
- Tomkiel JE, Alansari H, Tang N, Virgin JB, Yang X, VandeVord P, Karvonen RL, Granda JL, Kraut MJ, Ensley JF, Fernandez-Madrid F. Autoimmunity to the M(r) 32,000 subunit of replication protein A in breast cancer. Clin Cancer Res. 8: 752-8, 2002.
- ZC Cui, KL Ma, XB Zhang, and NM Tang. Effects of Ganglioside GM3 on
- Phospholipid Turnover of Human Leukemic J6-2 Cells. Neurochemical Research, 27: 771-778, 2002.
- Seyfried DM, Veyna R, Han Y, Li K, Tang, NM, Betts RL, Weinsheimer S, Chopp M, Anagli J. A selective cysteine protease inhibitor is non-toxic and erebroprotective in rats undergoing transient middle cerebral artery ischemia. Brain Res. 901: 94-101, 2001.
- Tang NM, Dong HW, Wang XM, Tsui ZC, Han JS. Cholecystokinin antisense RNA increases the analgesic effect induced by electro-acupuncture or low dose morphine: conversion of low responder rats into high responders. Pain, 78:71-80, 1997.
- Tang NM, Dong HW, Wang XM, Tsui ZC, Han JS. CCK antisense RNA could reverse nonresponder to responder on 100Hz electroacupuncture analgesia. Chinese J. of Pain. 1: 45-48, 1996. (Chinese).
- XB Zhang, NM Tang, Q Xia, ZM Zhu, ZC Tsui. Effect of differentiation inducers on the lectin binding capacity of a human monocytoid J6-2 leukemic cells and on the incorporation of [125I] UdR into the cells. Chinese J Pathophysiol, 11: 582-586, 1995 (Chinese).
- NM Tang, XM Wang, JS Han. A simple and efficient method for preparation of plasmid DNA. Life Chemistry, 8: 35. 1995. (Chinese).
- NM Tang, HW Dong, XM Wang, ZC Tsui, JS Han. Effect of CCK sense and antisense RNA on low-lose morphine analgesia of rats. Chin Sci Bul, 11: 156-158, 1994. (Chinese).
- NM Tang, SY Sun, BB Ke, J Tang. Expression of TGF-2 gene in cardiovascular
- diseases. Chin Biochem J, 10: 30-33, 1994.(Chinese).
- NM Tang, XB Zhang, ZM Zhu, ZC Cui. Studies on glycosphingolipid changes in carbon tetrachlorideintoxicated rat liver. Chin J Ind Hyg Occup Dis, 12: 269-271, 1994;(Chinese).
- NM Tang, YDYong, BB Ke, J Tang. Expression of vascular endothelial growth factor in atherosclerotic plaques of rabbits. J of Beijing Medical University, 106: 471-473, 1993. (Chinese).